中文名氟苯咪唑英文名Flubendazole别名氟苯咪唑氟苯哒唑氟化甲苯哒唑氟苯达唑杂质氟苯咪唑原料药氟苯达唑 标准品氟苯达唑溶液,100PPM氟苯咪唑溶液, 100PPM5-(4-氟苯甲酰基)苯并咪唑-2-氧基甲酸甲酯[5-(4-氟苯甲酰)-1H-苯并咪唑-2-基]氨基甲酸甲酯英文别名FLUBENOLFLUMOXALFLUMOXANEFLUMOXANALFLUBENDAZOLFLUBENDAZOLEFlubendazoleMETHYL [5-(4-FLUOROBENZOYL)-1H-BENZIMIDAZOL-2-YL]CARBAMATEmethyl [6-(4-fluorobenzoyl)-1H-benzimidazol-2-yl]carbamatemethyl N-[5-(4-fluorobenzoyl)-3H-benzoimidazol-2-yl]carbamate[5-(4-FLUOROBENZOYL)-1H-BENZIMIDAZOL-2-YL]CARBAMIC ACID, METHYL ESTERCARBAMIC ACID, [5-(4-FLUOROBENZOYL)-1H-BENZIMIDAZOL-2-YL]-METHYL ESTERCAS31430-15-6EINECS250-624-4化学式C16H12FN3O3分子量313.28InChIInChI=1/C16H12FN3O3/c1-23-16(22)20-15-18-12-7-4-10(8-13(12)19-15)14(21)9-2-5-11(17)6-3-9/h2-8H,1H3,(H2,18,19,20,22)密度1.3720 (estimate)熔点290°C沸点°Cat760mmHg溶解度Practically insoluble in water, in alcohol and in methylene chloride折射率1.685酸度系数10.66±0.10(Predicted)存储条件2-8°C外观neat颜色White to Off-WhiteMerck14,4118MDL号MFCD00871999体外研究在Echinococcus granulosus中,Flubendazole形态变化包括SOMA区收缩,皮层泡形成,rostellar混乱,钩损和microtriches破坏。 Flubendazole的苯环已结合在杂环(咪唑)的-4和-5位置的双环体系。 Flubendazole和Albendazole对大鼠胚胎发育在体外培养有相似的影响,在浓度高于0.5 μg/mL时诱导生长停滞和改变形态的作用。