中文名泼尼松英文名prednisone别名强的松泼尼松去氢可的松泼尼松原料药泼尼松的原料药泼尼松片 标准品湖北泼尼松原料药泼尼松, 对照品英文别名CortanColisoneBicortoneAncortoneprednisonePrednisone1,2-Dehydrocortisone11,20-trione,17,21-hydroxy-pregna-4-diene-311,20-trione,17,21-dihydroxy-pregna-4-diene-31,4-pregnadiene-16-alpha,21-diol-3,11,20-trione17-alpha,21-dihydroxypregna-1,4-diene-3,11,20-trione(8xi,9xi,14xi)-17,21-dihydroxypregna-1,4-diene-3,11,20-trioneCAS53-03-2EINECS200-160-3化学式C21H26O5分子量358.43InChIInChI=1/C21H26O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h5,7,9,14-15,18,22,26H,3-4,6,8,10-11H2,1-2H3/t14?,15?,18?,19-,20-,21-/m0/s1密度1.1121 (rough estimate)熔点236-238°C(lit.)沸点410.86°C (rough estimate)比旋光度169 º (c=0.5, dioxane)闪点>200℃水溶性115mg/L(25 ºC)蒸汽压1.51E-15mmHg at 25°C溶解度Practically insoluble in water, slightly soluble in ethanol (96 per cent) and in methylene chloride. It shows polymorphism (5.9).折射率170 ° (C=0.5, Dioxan酸度系数12.36±0.60(Predicted)存储条件2-8°C稳定性Stable. Incompatible with strong oxidizing agents.外观Solid颜色White to Off-WhiteMerck7722BRN2065301物化性质白色或类白色结晶性粉末,无气味,味微苦。几乎不溶于水,微溶于乙醇(1:190)和氯仿(1:200)。Mp233-235℃(分解),比旋光度[α]25D+172°(二噁烷),本品乙酸溶液在240nm波长处有最大吸收。