研发生产克卓替尼 克唑替尼 可唑替尼CAS: 877399-52-5原料生产供应仅供企业出口现货直销

中文名克里唑蒂尼英文名3-[1-(2,6-Dichloro-3-fluoro-phenyl)-ethoxy]-5-(1-piperidin-4-yl-1H-pyrazol-4-yl)-pyridin-2-ylamine别名克卓替尼克唑替尼可唑替尼克里唑啼尼克里唑替尼克里唑蒂尼CRIZO锡IBC-MET和ALK抑制剂(CRIZOTINIB)3-[1-(2,6-二氯-3-氟-苯基)-乙氧基]-5-(1-哌啶-4-基-1H-吡唑-4-基)-吡啶-2-基胺(R)-3-(1-(2,6-二氯-3-氟苯基)乙氧基)-5-(1-(哌啶-4-基)-1H-吡唑-4-基)吡啶-2-胺3-[(R)-1-(2,6-二氯-3-氟苯基)乙氧基]-5-[1-(哌啶-4-基)-1H-吡唑-4-基]吡啶-2-胺英文别名XalkoriPF2341066CrizotinibCrozotinibCrizotinib XalkoriCrizotinib,PF-02341066(5-(pyridin-3-yl)-1,3,4-oxadiazol-2-yl)methanamine3-[1-(2,6-Dichloro-3-fluoro-phenyl)-ethoxy]-5-(1-piperidin-4-yl-1H-pyrazol-4-yl)-pyridin-2-ylamine3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(4-piperidinyl)-1H-pyrazol-4-yl]-2-Pyridinamine3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(piperidin-4-yl)-1H-pyrazol-4-yl]pyridin-2-amine(R)-3-[1-(2,6-Dichloro-3-fluorophenyl)ethoxy]-5-(1-piperidin-4-yl-1H- pyrazol-4-yl)pyridin-2-ylaMine3-[(1R)-1-(2,6-Dichloro-3-fluorophenyl)ethoxy]-5-[1-(piperidin-4-yl)-1H-pyrazol-4-yl]-2-aMinopyridine2-PyridinaMine, 3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(4-piperidinyl)-1H-pyrazol-4-yl]-[3-[[(R)-1-(2,6-Dichloro-3-fluorophenyl)ethyl]oxy]-5-[1-(piperidin-4-yl)-1H-pyrazol-4-yl]pyridin-2-yl]aMineCAS877399-52-5EINECS638-814-9化学式C21H22Cl2FN5O分子量450.34InChIInChI=1/C21H22Cl2FN5O/c1-12(19-16(22)2-3-17(24)20(19)23)30-18-8-13(9-27-21(18)25)14-10-28-29(11-14)15-4-6-26-7-5-15/h2-3,8-12,15,26H,4-7H2,1H3,(H2,25,27)/t12-/m1/s1密度1.47±0.1 g/cm3(Predicted)熔点192 °C沸点599.2±50.0 °C(Predicted)闪点316.171°C蒸汽压0mmHg at 25°C溶解度Soluble in DMSO (up to 25 mg/ml with warming) or in Ethanol (up to 25 mg/ml with warming)折射率1.673酸度系数9.81±0.10(Predicted)存储条件room temp稳定性Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.外观powder颜色white to tan

---