中文名倍他米松英文名Betamethasone别名贝他美松β-美松倍他美松倍他米松培他美松倍他米松原料药倍他米松(标准品)倍他米松溶液, 100PPMBETAMETHASONE 倍他米松16b-甲基-11b,17a,21-三羟基-9a-孕甾-1,4-二烯-3,20-二酮英文别名Betamethasone17,21-trihydrBetamethasone baseBetamethasone (200 mg)BetaMethasone SolutioMbetamethasone standardBetaMethasone (Celestone)9alpha-fluoro-16beta-methylprednisolone9-fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione9a-fluoro-11b,17a,21-trihydroxy-16b-methylpregna-1,4-diene-3,20-dione(11beta,16alpha)-9-fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione(8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro- 11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl- 6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-oneBetamethasone,9α-Fluoro-11β,17α,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione, 9α-Fluoro-16β-methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione, 9α-Fluoro-16β-methylprednisoloneCAS378-44-9EINECS206-825-4化学式C22H29FO5分子量392.47InChIInChI=1/C22H29FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15+,16+,17+,19+,20+,21+,22+/m1/s1密度1.1283 (estimate)熔点235-237°C沸点568.2±50.0 °C(Predicted)比旋光度D +108° (acetone)闪点297.5°C水溶性58mg/L(25 ºC)蒸汽压2.81E-15mmHg at 25°C溶解度Practically insoluble in water, sparingly soluble in anhydrous ethanol, very slightly soluble in methylene chloride.折射率118 ° (C=1, Dioxane)酸度系数12.13±0.70(Predicted)存储条件0-6°C外观neat颜色White to Off-WhiteMerck14,1180物化性质白色结晶性粉末。熔点231-234℃(分解)。无臭。醋酸倍他米松([987-24-6])亦为白色结晶性粉末,熔点205-208℃,微溶于丙醇、乙醇,极难溶于氯仿或yimi,不溶于水,无臭。体外研究Betamethasone对II型糖皮质激素受体具有特异亲合力,存在于大多数脑区。