中文名盐酸氯己定英文名Chlorhexidine dihydrochloride别名盐酸洗必泰盐酸氯己定洗必泰盐酸盐氯己定.2盐酸氯己定二盐酸盐盐酸氯己定 标准品双氯苯双胍己烷 二盐酸盐双氯苯双胍己烷.2HCL1,1'-己基双[5-(对氯苯基)双胍]盐酸盐盐酸氯己定,1,1'-己基双[5-(对氯苯基)双胍]盐酸盐英文别名ArlacideHChlorhexidine HydrochlorideChlorhexidini HydrochlorideChlorhexidine dihydrochloride2,4,11,13-Tetraazatetradecanediimidamide1,1'-hexamethylenebis(5-(p-chlorophenyl)-biguaniddihydrochloride1,1'-Hexamethylenebis(5-(p-chlorophenyl)biguanide) dihydrochlorideBiguanide,1,1'-hexamethylenebis[5-(p-chlorophenyl)-,dihydrochlorideBiguanide, 1,1'-hexamethylenebis(5-(p-chlorophenyl)-, dihydrochloride2,4,11,13-tetraazatetradecanediimidamide,n,n''-bis(4-chlorophenyl)-3,12-diimin2,2'-hexane-1,6-diylbis(1-{amino[(4-chlorophenyl)amino]methylidene}guanidine) dihydrochloride2,4,11,13-Tetraazatetradecanediimidamide,N,N''-bis(4-chlorophenyl)-3,12-diimino-,dihydrochloride2,4,11,13-Tetraazatetradecanediimidamide, N,N'-bis(4-chlorophenyl)-3,12-diimino-, dihydrochlorideCAS3697-42-5EINECS223-026-6化学式C22H32Cl4N10分子量578.37InChIInChI=1/C22H30Cl2N10.2ClH/c23-15-5-9-17(10-6-15)31-21(27)33-19(25)29-13-3-1-2-4-14-30-20(26)34-22(28)32-18-11-7-16(24)8-12-18;;/h5-12H,1-4,13-14H2,(H5,25,27,29,31,33)(H5,26,28,30,32,34);2*1HInChIKeyWJLVQTJZDCGNJN-UHFFFAOYSA-N密度1.284[at 20℃]熔点111-116°C沸点699.3°C at 760 mmHg闪点376.7°C水溶性0.06 g/100 mL (20 ºC)蒸汽压0.003Pa at 25℃溶解度Sparingly soluble in water and in propylene glycol, very slightly soluble in ethanol (96 per cent).存储条件2-8°C外观neat颜色White to Off-WhiteMerck14,2091物化性质性状:白色或几乎白色结晶性粉末;无臭,味苦。熔点 111-116 °C储存条件 2-8°C水溶解性 0.06 g/100 mL (20 oC)MDL号MFCD00068998体外研究Chlorhexidine是一种化学防腐剂。尽管它对一些革兰氏阴性菌疗效较低,但它对革兰氏阳性和革兰氏阴性菌均有效。它既具有杀菌,也具有抑菌的作用机制,作用机制为细胞膜干扰,而不是ATPase灭活。它也对真菌和包膜病毒有效,尽管该作用未被广泛研究。Chlorhexidine在高浓度下是有害的,但是在许多产品中低浓度下是安全的,比如漱口水和隐形眼镜护理液。