研发生产新橙皮苷(neohesperidin) CAS: 13241-33-3原料药研发供应中间体现货直销

中文名新橙皮苷英文名neohesperidin别名桔皮苷柑果苷新桔皮苷新橙皮甙新橙皮苷新陈皮苷新橙皮苷(标准品)新橙皮苷, 来源于枳新橙皮甙,柑果苷,桔皮苷,新陈皮苷英文别名neohesperidinHESPERETIN-7-NEOHESPERIDOSIDEHESPERETIN-7-O-NEOHESPERIDOSIDE(s)-a-d-glucopyranosyl)oxy)-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)4h-1-benzopyran-4-one,2,3-dihydro-7-((2-o-(6-deoxy-alpha-l-mannopyranosyl)-bet(S)-4-Methoxy-3,5,7-trihydroxyflavanone-7-[O-(alpha-L-rhamnopyranosyl)-beta-D-glucopyranoside5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-oxo-3,4-dihydro-2H-chromen-7-yl 2-O-(6-deoxyhexopyranosyl)hexopyranoside(2S)-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-oxo-3,4-dihydro-2H-chromen-7-yl 2-O-(6-deoxy-L-mannopyranosyl)-beta-D-glucopyranoside(2S)-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-oxo-3,4-dihydro-2H-chromen-7-yl 2-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranoside7-[[4,5-dihydroxy-6-(hydroxymethyl)-3-[(3,4,5-trihydroxy-6-methyl-2-oxanyl)oxy]-2-oxanyl]oxy]-5-hydroxy-2-(3-hydroxy-5-methoxyphenyl)-3,4-dihydro-2H-1-benzopyran-4-oneCAS13241-33-3EINECS236-216-9化学式C28H34O15分子量610.56InChIInChI=1/C28H34O15/c1-10-21(33)23(35)25(37)27(39-10)43-26-24(36)22(34)19(9-29)42-28(26)40-12-6-14(31)20-15(32)8-17(41-18(20)7-12)11-3-4-16(38-2)13(30)5-11/h3-7,10,17,19,21-31,33-37H,8-9H2,1-2H3/t10-,17-,19+,21-,22+,23+,24-,25+,26+,27-,28+/m0/s1InChIKeyARGKVCXINMKCAZ-RTFRIYMLSA-N密度1.65±0.1 g/cm3(Predicted)熔点239-243°C沸点933.7±65.0 °C(Predicted)比旋光度-100 (c, 0.5 in Py)闪点306.7°C水溶性3.98mg/L at 20℃蒸汽压0Pa at 20℃溶解度DMSO (Slightly), Pyridine (Slightly)折射率1.695酸度系数7.14±0.40(Predicted)存储条件Sealed in dry,2-8°C敏感性Sensitive to light外观neat颜色White to Off-WhiteBRN74945物化性质白色粉末，易溶于甲醇，几乎不溶于yimi，来源于枳壳，酸橙幼果，柑橘。MDL号MFCD16661259体外研究Neohesperidin，一种在柑橘类水果中发现的黄酮糖苷，是一种抗氧化剂。在1,1-diphenyl-2-picryldydrazyl (DPPH) 自由基清除试验中，Neohesperidin作为抗氧化剂，IC50为22.31微克/毫升。Neohesperidin (50 毫克/千克)显著抑制HCl/乙醇诱导的胃损伤，并且增加粘液含量。在幽门结扎的大鼠体内，neohesperidin (50毫克/千克)显著减少胃分泌液和胃酸产生的量，并且升高PH值。此外，Neohesperidin抑制Caco-2，CEM/ADR5000和CCRF-CEM白血病细胞的生长，IC50 值分别为0.17，0.17以及0.12 mM。

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