研发生产阿哥美拉汀 阿戈美拉汀 阿戈美伐汀CAS: 138112-76-2原料供应发货仅供科研实验现货直销

中文名阿戈美拉汀英文名Agomelatine别名阿哥美拉汀阿戈美拉汀阿戈美伐汀阿戈美拉汀及中间体阿戈美拉汀(晶型I,II)阿戈美拉汀, 一种5-HT2C受体竞争性拮抗剂N-[2-(7-甲氧基萘-1-基)乙基]乙酰胺英文别名CS-1963S 20098MelitorVALDOXANMELITORTHYMANAXAGOMELATIN138112-76-2AgomelatineAglomelatineAgoMelatine(S-20098,Valdoxan)N-[2-(7-Methoxy-1-naphthyl)ethyl]acetamideN-[2-(7-methoxynaphthalen-1-yl)ethyl]acetamideAcetamide, N-(2-(7-methoxy-1-naphthalenyl)ethyl)-S20098,N-[2-(7-Methoxynaphth-1-yl)ethyl]acetamideCAS138112-76-2EINECS629-727-7化学式C15H17NO2分子量243.3InChIInChI=1/C11H14N4O2.CH4O3S/c1-5-2-9(16)7-3-8(14-15-11(12)13)10(17)4-6(5)7;1-5(2,3)4/h3-5,9,16H,2H2,1H3,(H4,12,13,15);1H3,(H,2,3,4)/b14-8-InChIKeyYJYPHIXNFHFHND-UHFFFAOYSA-N密度1.109±0.06 g/cm3(Predicted)熔点107-109°C沸点478.8±28.0 °C(Predicted)溶解度DMSO: >50 mg/mL酸度系数16.17±0.46(Predicted)存储条件2-8°C外观粉末颜色white to off-whiteMerck14,190MDL号MFCD00916659体外研究在慢性应激电击的小鼠的海马中，Agomelatine完全正常化压力影响的细胞生存并部分逆转降低的doublecortin表达。