研发生产缬沙坦 缬沙坦相关物A (R)-缬沙坦CAS: 137862-53-4原料供应发货仅供科研实验现货直销

中文名缬沙坦英文名Valsartan别名缬沙坦缬沙坦相关物A(R)-缬沙坦缬沙坦EP杂质A缬沙坦相关物质A盐酸氨溴索杂质D缬沙坦(标准品)缬沙坦相关化合物A缬沙坦USP相关物质A原研CGP 49309缬沙坦(盐酸氨溴索杂质D)缬沙坦溶液, 100PPM缬沙坦, 一种非肽类血管紧张素II AT1受体拮抗剂N-(1-戊酰基)-N-[4-[2-(1H-四氮唑-5-基)苯基]苄基]-L-缬氨酸N-戊酰基-N-[[2'-(1H-四唑-5-基)[1,1'-联苯]-4-基]甲基]-D-缬氨酸N-((2'-(1H-四唑-5-基)-[1,1'-联苯]-3-基)甲基)-N-戊酰基-L-缬氨酸N-(1-氧代戊基)-N-[[2'-(1H-四氮唑-5-基)[1,1'-联苯]-3-基]甲基]-L-缬氨酸(R)-2-(N-((2'-(1H-四唑-5-基)-[1,1'-联苯]-4-基)甲基)戊氨基)-3 - 甲基丁酸英文别名Valsartanent-ValsartanVALSARTAN IMP CValsartan(Diovan)Valsartan R-enantiomerValsartan Related Compound AAmbroxol Hydrochloride Imp.D(R)-2-(N-((2'-(1H-tetrazol-5-yl)N-pentanoyl-N-{[2'-(2H-tetrazol-5-yl)biphenyl-4-yl]methyl}valine(S)-N-Valeryl-N-([2'-(1H-tetrazole-5-yl)biphen-4-yl]methyl)valineN-pentanoyl-N-{[2'-(2H-tetrazol-5-yl)biphenyl-4-yl]methyl}-L-valineN-pentanoyl-N-{[2'-(2H-tetrazol-5-yl)biphenyl-4-yl]methyl}-D-valineN-((2'-(1H-Tetrazol-5-yl)-[1,1'-biphenyl]-3-yl)methyl)-N-pentanoyl-L-valineN-(1-Oxopentyl)-N-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-3-yl]methyl]-L-valineN-(1-OXOPENTYL)-N-[[2'-(1H-TETRAZOL-5-YL)[1,1'-BIPHENYL]-4-YL]METHYL]-L-VALINEL-Valine, N-(1-oxopentyl)-N-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-L-VALINE,N-(1-OXOPENTYL)-N-[[2''-(1H-TETRAZOL-5-YL)[1,1''-BIPHENYL]-3-YL]METHYL]-(R)-2-[N-[[2'-(5-Tetrazolyl)-4-biphenylyl]methyl]pentanamido]-3-methylbutanoic AcidD-Valine, N-(1-oxopentyl)-N-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]- (9CI)L-Valine, N-(1-oxopentyl)-N-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-3-yl]methyl]- (9CI)3-Methyl-2-[pentanoyl-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]amino]-butanoic aci3-methyl-2-[pentanoyl-[[4-[2-(2h-tetrazol-5-yl)phenyl]phenyl]methyl]amino]-butanoic acid(S)-2-(N-((2'-(1H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)pentanamido)-3-methylbutanoic aci(R)-2-(N-((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)pentanamido)-3-methylbutanoic acid(S)-N-(1-carboxy-2-methyl-prop-1-yl)-N-pentanoyl-N-[(2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl]amineCAS137862-53-4137863-60-6137862-87-4EINECS1592732-453-0化学式C24H29N5O3分子量435.52InChIInChI=1/C24H29N5O3/c1-4-5-10-21(30)29(22(16(2)3)24(31)32)15-17-11-13-18(14-12-17)19-8-6-7-9-20(19)23-25-27-28-26-23/h6-9,11-14,16,22H,4-5,10,15H2,1-3H3,(H,31,32)(H,25,26,27,28)/t22-/m1/s1InChIKeyACWBQPMHZXGDFX-QFIPXVFZSA-N密度1.212±0.06 g/cm3(Predicted)熔点116-117°C沸点684.9±65.0 °C(Predicted)闪点368°C水溶性84.99mg/L(25 ?C)蒸汽压1.06E-19mmHg at 25°C溶解度DMSO: ≥ 20 mg/mL折射率1.586酸度系数3.56±0.10(Predicted)存储条件2-8°C稳定性吸湿性敏感性Easily absorbing moisture外观粉末颜色white to tanMerck14,9916物化性质从二异丙醚结晶，熔点116--117℃。MDL号MFCD00865840体外研究Valsartan剂量依赖性抑制血管紧张素II诱导的血管收缩，降低高血压的肾素依赖性模型的血压。Valsartan是至少一样有效的ACE抑制剂，利尿剂，β-阻断剂和钙拮抗剂。